Article
The role of cysteine residues in S100B dimerization and regulation of target protein activity.
Biochimica et biophysica acta - 14 Nov 1997
Landar A, Hall T L, Cornwall E H, Correia J J, Drohat A C, Weber D J, Zimmer D B
Abstract excerpt
Previous studies have demonstrated that the two cysteine residues in the calcium-binding protein S100B are required for its extracellular functions. In the present study, a recombinant S100B protein and mutant S100Bs containing one or no cysteine residue(s) have been used to determine the contrib...
Topics
- Calcium-Binding Proteins
- Cysteine
- Dimerization
- Mutation
- Nerve Growth Factors
- Recombinant Proteins
- S100 Calcium Binding Protein beta Subunit
- S100 Proteins