Article

High throughput competitive fluorescence polarization assay reveals functional redundancy in the S100 protein family

2019-07-29

Abstract excerpt

The calcium-binding, vertebrate-specific S100 protein family consists of 20 paralogs in humans (referred as the S100ome), with several clinically important members. To assess their interactome, high-throughput, systematic analysis is indispensable, which allows one to get not only qualitative but quantitative insight into their protein-protein interactions (PPIs). We have chosen an unbiased assay, fluorescence pol...

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Literature Corpus work: d9e30b05-feaf-5a4a-be3b-87ad831626e7
DOI: 10.1101/718155

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