Article
Neonatal fulminant hepatitis B: structural and functional analysis of complete hepatitis B virus genomes from mother and infant.
The Journal of infectious diseases - 1 May 1998
Sterneck M, Kalinina T, Otto S, Günther S, Fischer L, Burdelski M, Greten H, Broelsch C E, Will H
Abstract excerpt
Transmission of hepatitis B virus (HBV) from anti-hepatitis B e (anti-HBe)-positive carrier mothers to their infants may result in neonatal fulminant hepatitis B (FHB). We investigated whether HBV variants with a particular DNA sequence and functional phenotype, responsible for FHB, are selected during transmission. Full-length HBV genomes from a mother-infant pair were completely sequenced and transfected into...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
