Article
Neonatal fulminant hepatitis B: structural and functional analysis of complete hepatitis B virus genomes from mother and infant.
The Journal of infectious diseases - 1 May 1998
Sterneck M, Kalinina T, Otto S, Günther S, Fischer L, Burdelski M, Greten H, Broelsch C E, Will H
Abstract excerpt
Transmission of hepatitis B virus (HBV) from anti-hepatitis B e (anti-HBe)-positive carrier mothers to their infants may result in neonatal fulminant hepatitis B (FHB). We investigated whether HBV variants with a particular DNA sequence and functional phenotype, responsible for FHB, are selected...
Topics
- Adult
- Base Sequence
- DNA, Viral
- Female
- Genetic Variation
- Genome, Viral
- Hepatitis B
- Hepatitis B virus
- Humans
- Infant, Newborn
- Infectious Disease Transmission, Vertical
- Polymerase Chain Reaction
- Pregnancy
- Pregnancy Complications, Infectious
- Sequence Alignment