Article
A human glucagon-like peptide-1 receptor polymorphism results in reduced agonist responsiveness.
Regulatory peptides - 15 Aug 2005
Beinborn Martin, Worrall Christine I, McBride Edward W, Kopin Alan S
Abstract excerpt
Glucagon-like peptide-1 (GLP-1) and its cognate receptor play an important physiological role in maintaining blood glucose homeostasis. A GLP-1 receptor (GLP-1R) polymorphism in which threonine 149 is substituted with a methionine residue has been recently identified in a patient with type 2 diab...
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