Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rapid and nonisotopic SSCP-based analysis of the BAT-26 mononucleotide repeat for identification of the replication error phenotype in human cancers.

Human mutation - 1 Jan 1998

Iacopetta B, Hamelin R

Abstract excerpt

Microsatellite instability is an important new form of genetic alteration that characterizes tumors of the replication error phenotype (RER+). The RER status of tumors has been determined until now by analyzing several microsatellite loci for size variations compared with matching normal DNA. This has been done by separating isotopically labeled PCR products on denaturing gels. We recently showed that deletions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA-Binding Proteins
Share to DNA, Neoplasm
Share to DNA Replication

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Electrophoresis, Polyacrylamide Gel

Share to Phenotype

Share to Polymerase Chain Reaction

Share to Polymorphism, Single-Stranded Conformational

Share to Sequence Deletion

Source

Identifiers

PMID: 9792412
DOI: 10.1002/(SICI)1098-1004(1998)12:5<355::AID-HUMU9>3.0.CO;2-C

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rapid and nonisotopic SSCP-based analysis of the BAT-26 mononucleotide repeat for identification of the replication error phenotype in human cancers.PMID 9792412Read ↗

Routine detection of the replication error phenotype in clinical tumor specimens using fluorescence-SSCP.Semantic proximity Read ↗

Determination of the replication error phenotype in human tumors without the requirement for matching normal DNA by analysis of mononucleotide repeat microsatellites.Semantic proximity Read ↗

BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines.Semantic proximity Read ↗

Allelic profiles of mononucleotide repeat microsatellites in control individuals and in colorectal tumors with and without replication errors.Semantic proximity Read ↗

Gastric carcinomas with microsatellite instability: clinical features and mutations to the TGF-beta type II receptor, IGFII receptor, and BAX genes.Semantic proximity Read ↗

Mononucleotide repeats BAT-26 and BAT-25 accurately detect MSI-H tumors and predict tumor content: implications for population screening.Semantic proximity Read ↗

Genomic instability and target gene mutations in colon cancers with different degrees of allelic shifts.Semantic proximity Read ↗

Multiple epithelial and nonepithelial tumors in hereditary nonpolyposis colorectal cancer: characterization of germline and somatic mutations of the MSH2 gene and heterogeneity of replication error phenotypes.Semantic proximity Read ↗

Fluorescent-based BAT-26 analysis for distinct screening of microsatellite instability in colorectal cancers.Semantic proximity Read ↗

Frequency and prognostic impact of microsatellite instability in a large population-based study of endometrial carcinomas.Semantic proximity Read ↗

Diverse hypermutability of multiple expressed sequence motifs present in a cancer with microsatellite instability.Semantic proximity Read ↗

Mutation analysis of the transforming growth factor-beta type II receptor in human cell lines resistant to growth inhibition by transforming growth factor-beta.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.