Rapid and nonisotopic SSCP-based analysis of the BAT-26 mononucleotide repeat for identification of the replication error phenotype in human cancers.

doi:10.1002/(SICI)1098-1004(1998)12:5<355::AID-HUMU9>3.0.CO;2-C

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Article

Rapid and nonisotopic SSCP-based analysis of the BAT-26 mononucleotide repeat for identification of the replication error phenotype in human cancers.

Human mutation - 1 Jan 1998

Iacopetta B, Hamelin R

Abstract excerpt

Microsatellite instability is an important new form of genetic alteration that characterizes tumors of the replication error phenotype (RER+). The RER status of tumors has been determined until now by analyzing several microsatellite loci for size variations compared with matching normal DNA. Thi...

Topics

DNA Replication
DNA, Neoplasm
DNA-Binding Proteins
Electrophoresis, Polyacrylamide Gel
Humans
Microsatellite Repeats
MutS Homolog 2 Protein
Neoplasms
Phenotype
Poly A
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Proto-Oncogene Proteins
Sequence Deletion

Source

Open in PubMed

Identifiers

PMID: 9792412
DOI: 10.1002/(SICI)1098-1004(1998)12:5<355::AID-HUMU9>3.0.CO;2-C

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9792412-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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