Diverse hypermutability of multiple expressed sequence motifs present in a cancer with microsatellite instability.

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Article

Diverse hypermutability of multiple expressed sequence motifs present in a cancer with microsatellite instability.

Oncogene - 4 Apr 1996

Eshleman J R, Markowitz S D, Donover P S, Lang E Z, Lutterbaugh J D, Li G M, Longley M, Modrich P, Veigl M L, Sedwick W D

Abstract excerpt

Colon cancer and an increasing number of other cancers have been found to exhibit instability of DNA microsatellite sequences. Such tumors have been designated as replication errors (RER) tumors. However, as microsatellites are only rarely found within coding regions of the genome, instability of...

Topics

Base Sequence
Cell Line
Colonic Neoplasms
DNA Repair
DNA Replication
DNA, Satellite
Humans
Hypoxanthine Phosphoribosyltransferase
Microsatellite Repeats
Molecular Sequence Data
Mutation
RNA Splicing

Source

Open in PubMed

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PMID: 8622858

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8622858-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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