Article
Fluorescent-based BAT-26 analysis for distinct screening of microsatellite instability in colorectal cancers.
International journal of oncology - 1 Apr 2003
Morifuji Masahiko, Hiyama Eiso, Murakami Yoshiaki, Imamura Yuji, Sueda Taijiro, Yokoyama Takashi
Abstract excerpt
For easy screening of genetic instability in colorectal cancers, we tried BAT-26 and BAT-25 mononucleotide repeats using fluorescent analysis and evaluated their usefulness and problems compared with other markers: D5S346, D17S250, D2S123, and D2S391, D4S392 (located near BAT-26 and BAT-25 respectively). The high-frequency of MSI (MSI-H) tumours, defined as tumours having instability in more than two markers,...
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