Article
Gastric carcinomas with microsatellite instability: clinical features and mutations to the TGF-beta type II receptor, IGFII receptor, and BAX genes.
The Journal of pathology - 1 Mar 1999
Iacopetta B J, Soong R, House A K, Hamelin R
Abstract excerpt
The replication error phenotype (RER+) represents an important new form of genetic alteration characterized by widespread instability in repetitive nucleotide sequences. The aim of this study was to compare the features of RER+ gastric tumours with those of RER+ colonic tumours. RER status was determined by analysis of size alterations in the BAT-26 mononucleotide repeat microsatellite. Twelve of 121 (10 per...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
