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Article

Genomic instability and target gene mutations in colon cancers with different degrees of allelic shifts.

Genes, chromosomes & cancer - 1 Apr 2000

Percesepe A, Pedroni M, Sala E, Menigatti M, Borghi F, Losi L, Viel A, Genuardi M, Benatti P, Roncucci L, Peltomäki P, Ponz de Leon M

Abstract excerpt

Two grades (high and low) of microsatellite instability (MSI) are known, depending on the number of mutated markers and the amount of allelic shifts. Forty-two colorectal tumors, previously found to have high-degree MSI at dinucleotidic repeat loci, were revisited with BAT26, a mononucleotide marker, and the number of shifted bases were counted. Seven tumors, all with local stages at diagnosis, had < or =6-bp...

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Share to bcl-2-Associated X Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10719374

Genes

BAX
MSH6
MSH3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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