Article
3' end structure and rearrangements of EGFR in glioblastomas.
Genes, chromosomes & cancer - 1 Nov 1998
Eley G, Frederick L, Wang X Y, Smith D I, James C D
Abstract excerpt
Rearrangements of EGFR are known to occur in a significant fraction of glioblastomas, the most common and malignant form of central nervous system tumor. Although the consequences of these alterations have been described at the mRNA and protein level, little is known about human EGFR genomic sequ...
Topics
- 3' Untranslated Regions
- Alternative Splicing
- Base Sequence
- DNA, Neoplasm
- Exons
- Gene Amplification
- Genes, erbB-1
- Glioblastoma
- Humans
- Molecular Sequence Data
- Mutation
- Reverse Transcriptase Polymerase Chain Reaction
- Sequence Analysis, DNA
- Translocation, Genetic