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Article

Loss of heterozygosity on chromosome 6q27 and p53 mutations in epithelial ovarian cancer.

Medical oncology (Northwood, London, England) - 1 Jul 1998

Suzuki M, Saito S, Saga Y, Ohwada M, Sato I

Abstract excerpt

Loss of heterozygosity (LOH) in chromosome region 6q27 and p53 mutations were studied to attempt to clarify the genetic etiology of ovarian cancer, with particular reference to clear cell adenocarcinoma (CCC), which has a poor prognosis. 6q27 LOH in 70 epithelial ovarian cancer patients was exami...

Topics

Adenocarcinoma, Clear Cell
Adult
Age Distribution
Aged
Alleles
Chromosomes, Human, Pair 6
Female
Genes, p53
Humans
Loss of Heterozygosity
Middle Aged
Mutation
Ovarian Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 9789220
DOI: 10.1007/BF02989590

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9789220-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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