Article
Loss of heterozygosity on chromosome 6q27 and p53 mutations in epithelial ovarian cancer.
Medical oncology (Northwood, London, England) - 1 Jul 1998
Suzuki M, Saito S, Saga Y, Ohwada M, Sato I
Abstract excerpt
Loss of heterozygosity (LOH) in chromosome region 6q27 and p53 mutations were studied to attempt to clarify the genetic etiology of ovarian cancer, with particular reference to clear cell adenocarcinoma (CCC), which has a poor prognosis. 6q27 LOH in 70 epithelial ovarian cancer patients was examined using four restriction fragment length polymorphism markers located at 6q27; p53 mutations in tumor DNA were...
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