Article
Angiotensin II type 1 receptor gene polymorphism is associated with an increased vascular reactivity in the human mammary artery in vitro.
Journal of vascular research - 1 Jan 2000
Henrion D, Amant C, Benessiano J, Philip I, Plantefève G, Chatel D, Hwas U, Desmont J M, Durand G, Amouyel P, Lévy B I
Abstract excerpt
A gene polymorphism of the angiotensin II (AII) type 1 receptor has been described previously (A to C transversion at position 1166). Besides the epidemiological studies needed to determine a possible relationship between the polymorphism and some cardiovascular diseases, no study has been conducted to determine the impact of the polymorphism on vascular functions. At subthreshold concentrations, within the...
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