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Article

Gly460Trp alpha-adducin gene polymorphism and endothelial function in untreated hypertensive patients.

Journal of hypertension - 1 Nov 2007

Perticone Francesco, Sciacqua Angela, Barlassina Cristina, Del Vecchio Lucia, Signorello Maria Chiara, Dal Fiume Chiara, Andreozzi Francesco, Sesti Giorgio, Cusi Daniele

Abstract excerpt

OBJECTIVES: Endothelium-dependent vasodilatation is impaired in essential hypertension. Besides traditional and emerging cardiovascular risk factors, genetic factors may also promote deleterious alterations of endothelial physiology. The aim of the present study was to investigate the relationship between the 460Trp allele of ADD1 and endothelium-dependent vasodilation in 110 never-treated hypertensive patients....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17921817
DOI: 10.1097/HJH.0b013e3282ef3a50

Genes

ADD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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