Article
Angiotensin II type 1 receptor A1166C gene polymorphism is associated with an increased response to angiotensin II in human arteries.
Hypertension (Dallas, Tex. : 1979) - 1 Mar 2000
van Geel P P, Pinto Y M, Voors A A, Buikema H, Oosterga M, Crijns H J, van Gilst W H
Abstract excerpt
An adenine/cytosine (A/C) base substitution at position 1166 in the angiotensin II type 1 receptor (AT(1)R) gene is associated with the incidence of essential hypertension and increased coronary artery vasoconstriction. However, it is still unknown whether this polymorphism is associated with a difference in angiotensin II responsiveness. Therefore, we assessed whether the AT(1)R polymorphism is associated with...
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