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Article

Genetic contribution to the acute effects of angiotensin II type 1 receptor blockade.

Journal of hypertension - 1 Apr 2005

Spiering Wilko, Kroon Abraham A, Fuss-Lejeune Monique Jmj, de Leeuw Peter W

Abstract excerpt

OBJECTIVE: Clinical observations point towards heterogeneity in patients' responses to antihypertensive drugs. As our earlier work showed that angiotensin II (AngII) sensitivity is associated with the A1166C polymorphism of the AngII type 1 receptor (AT1R) gene, we conducted the present study in which the responses to acute AT1R blockade were evaluated. METHODS: After 7 days of low and high sodium diet, the...

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Identifiers

PMID: 15775779
DOI: 10.1097/01.hjh.0000163143.66965.06

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