Article
Is the A1166C polymorphism of the angiotensin II type 1 receptor involved in cardiovascular disease?
European heart journal - 1 Jul 1998
van Geel P P, Pinto Y M, Buikema H, van Gilst W H
Abstract excerpt
Peptides produced by the renin-angiotensin system play a major role in the development and progression of various cardiovascular diseases. One of these peptides, angiotensin II, is a potent vasoconstrictor that exerts most of its effects through the human AT1 receptor. Following the discovery of a functional variation in the angiotensin-converting enzyme gene, research has identified other genetic variations in...
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