Is the A1166C polymorphism of the angiotensin II type 1 receptor involved in cardiovascular disease?

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Article

Is the A1166C polymorphism of the angiotensin II type 1 receptor involved in cardiovascular disease?

European heart journal - 1 Jul 1998

van Geel P P, Pinto Y M, Buikema H, van Gilst W H

Abstract excerpt

Peptides produced by the renin-angiotensin system play a major role in the development and progression of various cardiovascular diseases. One of these peptides, angiotensin II, is a potent vasoconstrictor that exerts most of its effects through the human AT1 receptor. Following the discovery of...

Topics

Animals
Cardiovascular Diseases
Gene Expression
Genetic Variation
Humans
Hypertension
Myocardium
Peptidyl-Dipeptidase A
Polymorphism, Genetic
Rats
Receptor, Angiotensin, Type 1
Receptor, Angiotensin, Type 2
Receptors, Angiotensin

Source

Open in PubMed

Identifiers

PMID: 9717050

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9717050-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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