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Article

Angiotensin II AT1 receptor constitutive activation: from molecular mechanisms to pathophysiology.

Molecular and cellular endocrinology - 29 Apr 2009

Petrel Christophe, Clauser Eric

Abstract excerpt

Mutations activating the angiotensin II AT(1) receptor are important to identify and characterize because they give access to the activation mechanisms of this G protein coupled receptor and help to characterize the signaling pathways and the potential pathophysiology of this receptor. The different constitutively activated mutations of the AT(1) receptor are mostly localized in transmembrane domains (TM) and...

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PMID: 19061936
DOI: 10.1016/j.mce.2008.10.049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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