Article
Molecular Pathology: Predictive, Prognostic, and Diagnostic Markers in Lymphoid Neoplasms.
Surgical pathology clinics - 1 Sept 2016
Ho Caleb, Kluk Michael J
Abstract excerpt
Lymphoid neoplasms show great diversity in morphology, immunophenotypic profile, and postulated cells of origin, which also reflects the variety of genetic alterations within this group of tumors. This review discusses many of the currently known genetic alterations in selected mature B-cell and T-cell lymphoid neoplasms, and their significance as diagnostic, prognostic, and therapeutic markers. Given the rapidly...
Topics
- Biomarkers, Tumor
- Gene Expression Regulation, Neoplastic
- Humans
- Leukemia, Lymphoid
- Lymphoma
- Mutation
- Pathology, Molecular
- Predictive Value of Tests
- Prognosis
