Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of CYP2E1 genotype in renal cell and urothelial cancer patients.

Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie - 1 Sept 1998

Farker K, Lehmann M H, Oelschlägel B, Haerting J, Hoffmann A, Janitzky V, Schubert J

Abstract excerpt

Genetic polymorphisms of enzymes involved in carcinogen metabolism have been found to influence susceptibility to cancer. Ethanol-inducible CYP2E1 is an enzyme of major toxicological interest because it metabolizes several drugs, precarcinogens and solvents to reactive metabolites. In the present study, we investigated the cytochrome P450 2E1 genetic polymorphism in renal cell/urothelial cancer patients from two...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Primers

Share to Genotype

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Share to Polymorphism, Restriction Fragment Length

Share to Risk Factors

Source

Identifiers

PMID: 9784018
DOI: 10.1016/S0940-2993(98)80029-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of CYP2E1 genotype in renal cell and urothelial cancer patients.PMID 9784018Read ↗

CYP2E1 genotyping in renal cell/urothelial cancer patients in comparison with control populations.Semantic proximity Read ↗

Cytochrome P450 2E1 variable number tandem repeat polymorphisms and health risks: a genotype-phenotype study in cancers associated with drinking and/or smoking.Semantic proximity Read ↗

Genetic polymorphism of cytochrome P450 2E1 in the Turkish population.Semantic proximity Read ↗

Role and importance of polymorphisms with respect to DNA methylation for the expression of CYP2E1 enzyme.Semantic proximity Read ↗

Analysis of point mutation in exon 2 of CYP2E1 gene in renal cell/urothelial cancer patients in comparison with control population.Semantic proximity Read ↗

Different regulation and expression of the human CYP2E1 gene due to the RsaI polymorphism in the 5'-flanking region.Semantic proximity Read ↗

Genetic polymorphisms and possible gene-gene interactions in metabolic and DNA repair genes: effects on DNA damage.Semantic proximity Read ↗

Impact of phase I or phase II enzyme polymorphisms on lymphocyte DNA adducts in subjects exposed to urban air pollution and environmental tobacco smoke.Semantic proximity Read ↗

RsaI polymorphism at the cytochrome P4502E1 locus and risk of hepatocellular carcinoma.Semantic proximity Read ↗

CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: comparison with aromatic/hydrophobic adduct formation.Semantic proximity Read ↗

Rsa I polymorphism at the cytochrome P4502E1 locus is not related to the risk of alcohol-related severe liver disease.Semantic proximity Read ↗

Glutathione transferase activities in renal carcinomas and adjacent normal renal tissues: factors influencing renal carcinogenesis induced by xenobiotics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.