Article
Role and importance of polymorphisms with respect to DNA methylation for the expression of CYP2E1 enzyme.
Gene - 15 Feb 2014
Naselli Flores, Catanzaro Irene, Bellavia Daniele, Perez Alessandro, Sposito Laura, Caradonna Fabio
Abstract excerpt
Different individuals possess slightly different genetic information and show genetically-determined differences in several enzyme activities due to genetic variability. Following an integrated approach, we studied the polymorphisms and methylation of sites contained in the 5' flanking region of the metabolizing enzyme CYP2E1 in correlation to its expression in both tumor and non-neoplastic liver cell lines,...
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