CYP2E1 genotyping in renal cell/urothelial cancer patients in comparison with control populations.

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Article

CYP2E1 genotyping in renal cell/urothelial cancer patients in comparison with control populations.

International journal of clinical pharmacology and therapeutics - 1 Sept 1998

Farker K, Lehmann M H, Kästner R, Hoffmann A, Janitzky V, Schubert J, Matz U, Hofmann W

Abstract excerpt

OBJECTIVE: Genetic polymorphisms in enzymes involved in carcinogen metabolism have been found to influence susceptibility to cancer. Ethanol-inducible CYP2E1 is an enzyme of major toxicological interest because it metabolizes several drugs, precarcinogens, and solvents to reactive metabolites. In...

Topics

Carcinoma, Renal Cell
Cytochrome P-450 CYP2E1
Genotype
Humans
Kidney Neoplasms
Polymorphism, Genetic
Risk Factors
Urologic Neoplasms
Urothelium

Source

Open in PubMed

Identifiers

PMID: 9760005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9760005-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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