Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphisms and possible gene-gene interactions in metabolic and DNA repair genes: effects on DNA damage.

Mutation research - 29 Jan 2006

Naccarati Alessio, Soucek Pavel, Stetina Rudolf, Haufroid Vincent, Kumar Rajiv, Vodickova Ludmila, Trtkova Katerina, Dusinska Maria, Hemminki Kari, Vodicka Pavel

Abstract excerpt

We investigated in a central European population, the association between genetic polymorphisms in several genes coding for xenobiotic metabolizing enzymes (CYP1A1, CYP2E1, EPHX1, GSTP1, GSTM1 and GSTT1) and in DNA repair genes (XPD, XPG, XPC and XRCC1) and the levels of single-strand breaks (SSBs) and SSB endonuclease III sensitive sites (endoIII sites) in peripheral blood lymphocytes. No significant differences...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to DNA Damage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Repair

Share to EPHX1 gene

Share to SSB gene

Share to XPC gene

Share to Genotype

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 16043197
DOI: 10.1016/j.mrfmmm.2005.06.016

Genes

EPHX1
SSB
GSTM1
GSTT1
GSTP1
XPC
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphisms and possible gene-gene interactions in metabolic and DNA repair genes: effects on DNA damage.PMID 16043197Read ↗

Chromosomal aberrations in tire plant workers and interaction with polymorphisms of biotransformation and DNA repair genes.Semantic proximity Read ↗

Markers of individual susceptibility and DNA repair rate in workers exposed to xenobiotics in a tire plant.Semantic proximity Read ↗

Influence of GSTM1, GSTT1, GSTP1, NAT1, NAT2, EPHX1, MTR and MTHFR polymorphism on chromosomal aberration frequencies in human lymphocytes.Semantic proximity Read ↗

Primary DNA damage and genetic polymorphisms for CYP1A1, EPHX and GSTM1 in workers at a graphite electrode manufacturing plant.Semantic proximity Read ↗

DNA adducts and combinations of multiple lung cancer at-risk alleles in environmentally exposed and smoking subjects.Semantic proximity Read ↗

Genetic polymorphisms and micronucleus formation: a review of the literature.Semantic proximity Read ↗

Association between genetic polymorphisms and biomarkers in styrene-exposed workers.Semantic proximity Read ↗

Occupational exposure to styrene: modulation of cytogenetic damage and levels of urinary metabolites of styrene by polymorphisms in genes CYP2E1, EPHX1, GSTM1, GSTT1 and GSTP1.Semantic proximity Read ↗

Impact of phase I or phase II enzyme polymorphisms on lymphocyte DNA adducts in subjects exposed to urban air pollution and environmental tobacco smoke.Semantic proximity Read ↗

Genetic polymorphisms of biotransformation enzymes: allele frequencies in the population of the Czech Republic.Semantic proximity Read ↗

Polymorphisms in DNA repair genes, chromosome aberrations, and lung cancer.Semantic proximity Read ↗

Genetic polymorphisms of biotransformation enzymes in patients with Hodgkin's and non-Hodgkin's lymphomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.