Article
Genetic polymorphism of cytochrome P450 2E1 in the Turkish population.
Cell biochemistry and function - 1 Dec 2001
Omer B, Ozbek U, Akköse A, Kiliç G
Abstract excerpt
CYP 2E1 is involved in metabolic activation of carcinogenic N-nitrosamines, benzene, urethane and other low molecular weight compounds. CYP2E1 gene is present in the population in various polymorphic forms. We detected the RFLP of the human CYP2E1 gene with the restriction endonuclease PstI, RsaI and DraI in a group of 153 Turkish individuals. According to the results of the PstI/RsaI analysis, 96.07% of the...
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