Article

S-phase checkpoint activity and function throughout the cell cycle

2017-01-01

Abstract excerpt

DNA damage or replication stress during S-phase can activate the S-phase checkpoint which executes a variety of responses, such as the inhibition of origin firing and replication fork stabilisation. Deregulation of the S-phase checkpoint leads to genomic instability, which has been implicated in diseases such as cancer. In this thesis, I aimed to address whether the S-phase checkpoint is regulated outside of S-pha...

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Literature Corpus work: 397398a6-0190-5151-a50a-e14a4c049bf1
DOI: 10.17863/cam.14717

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