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Article

Pathogenic role for virus-specific CD4 T cells in mice with coronavirus-induced acute encephalitis.

The American journal of pathology - 1 Jul 2006

Anghelina Daniela, Pewe Lecia, Perlman Stanley

Abstract excerpt

Acute viral encephalitis is believed to result from direct virus destruction of infected cells and from virus-induced host immune response, but the relative contribution of each remains largely unknown. For example, C57BL/6 (B6) mice infected with mouse hepatitis virus (JHM strain, JHMV) develop severe encephalitis, with death occurring within 7 days. Here, we show that the host response to a single JHMV-specific...

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Identifiers

PMID: 16816374
DOI: 10.2353/ajpath.2006.051308
PMCID: PMC1698761

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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