Hemagglutinin-esterase-specific monoclonal antibodies alter the neuropathogenicity of mouse hepatitis virus.

doi:10.1128/JVI.66.5.2865-2874.1992

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Article

Hemagglutinin-esterase-specific monoclonal antibodies alter the neuropathogenicity of mouse hepatitis virus.

Journal of virology - 1 May 1992

Yokomori K, Baker S C, Stohlman S A, Lai M M

Abstract excerpt

Some of mouse hepatitis virus strains contain an optional envelope glycoprotein, hemagglutinin-esterase (HE) protein. To understand the functional significance of this protein, monoclonal antibodies (MAbs) specific for this protein were generated and used for passive immunization of mice. None of these MAbs showed any virus-neutralizing activity in vitro; however, mice passively immunized with the purified MAbs...

Topics

Animals
Antibodies, Monoclonal
Astrocytoma
Brain
Cell Line
Central Nervous System
Demyelinating Diseases
Hemagglutinins, Viral
Hepatitis Viruses
Hepatitis, Viral, Animal
Immunization, Passive

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Inbred C57BL

Mutation

Spinal Cord

Survival Analysis

Viral Fusion Proteins

Viral Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 1560531
DOI: 10.1128/JVI.66.5.2865-2874.1992
PMCID: PMC241045

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1560531-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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