Article
Gyrase and Topo IV modulate chromosome domain size in vivo.
Molecular microbiology - 1 Sept 1998
Staczek P, Higgins N P
Abstract excerpt
In bacteria, DNA supercoil movement is restricted to subchromosomal regions or 'domains.' To elucidate the nature of domain boundaries, we analysed reaction kinetics for gammadelta site-specific resolution in six chromosomal intervals ranging in size from 14 to 90 kb. In stationary cultures of Sa...
Topics
- Chromosomes, Bacterial
- DNA Topoisomerase IV
- DNA Topoisomerases, Type II
- DNA, Bacterial
- DNA, Superhelical
- Genes, Bacterial
- Kinetics
- Models, Biological
- Mutation
- Salmonella typhimurium