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Article

Interactions of protein complexes on supercoiled DNA: the mechanism of selective synapsis by Tn3 resolvase.

Journal of molecular biology - 31 May 2002

Brown J Lesley, He Jiuya, Sherratt David J, Stark W Marshall, Boocock Martin R

Abstract excerpt

"Looping" interactions of distant sites on DNA molecules, mediated by DNA-binding proteins, feature in many regulated genetic processes. We used plasmids containing up to six res recombination sites for Tn3 resolvase to analyse looping interactions (synapsis) in this system. We observed that in plasmids with four or more res sites, certain pairs of sites recombine faster than others. The relative rates of...

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PMID: 12051914
DOI: 10.1016/S0022-2836(02)00309-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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