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Article

Growth rate toxicity phenotypes and homeostatic supercoil control differentiate Escherichia coli from Salmonella enterica serovar Typhimurium.

Journal of bacteriology - 1 Aug 2007

Champion Keith, Higgins N Patrick

Abstract excerpt

Escherichia coli and Salmonella enterica serovar Typhimurium share high degrees of DNA and amino acid identity for 65% of the homologous genes shared by the two genomes. Yet, there are different phenotypes for null mutants in several genes that contribute to DNA condensation and nucleoid formation. The mutant R436-S form of the GyrB protein has a temperature-sensitive phenotype in Salmonella, showing disruption...

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Identifiers

PMID: 17400739
DOI: 10.1128/JB.00083-07
PMCID: PMC1952050

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