Alterations of p53 gene and Ha-ras gene are independent events in solar keratosis and squamous cell carcinoma.

doi:10.1111/j.1440-1827.1998.tb03969.x

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Article

Alterations of p53 gene and Ha-ras gene are independent events in solar keratosis and squamous cell carcinoma.

Pathology international - 1 Sept 1998

Taguchi M, Tsuchida T, Ikeda S, Sekiya T

Abstract excerpt

In order to clarity the multiple-step progression from solar keratosis to squamous cell carcinoma, aberrations of the p53 gene (exons 2-11) and ras genes (exons 1 and 2) in solar keratosis and squamous cell carcinoma were investigated by polymerase chain reaction and single-strand conformation po...

Topics

Carcinoma, Squamous Cell
Genes, p53
Genes, ras
Humans
Keratosis
Mutation
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Sunlight

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