Article
A possible role for human papillomaviruses and c-myc, c-Ha-ras, and p53 gene alterations in malignant cutaneous lesions from renal transplant recipients.
Cancer detection and prevention - 1 Jan 1996
Pelisson I, Soler C, Chardonnet Y, Euvrard S, Schmitt D
Abstract excerpt
Several years after transplantation, renal transplant recipients develop numerous cutaneous squamous cell carcinomas (SCC), in which human papillomaviruses (HPV) may be detected. Alterations in c-myc, c-Ha-ras, and p53 genes were studied in 34 SCC, in correlation with the presence of HPV. In situ...
Topics
- Base Sequence
- Carcinoma, Squamous Cell
- Codon
- DNA, Viral
- Gene Amplification
- Genes, myc
- Genes, p53
- Genes, ras
- Humans
- Immunohistochemistry
- In Situ Hybridization
- Kidney Transplantation
- Molecular Sequence Data
- Mutation
- Papillomaviridae
- Skin Neoplasms
- Tumor Suppressor Protein p53