Article
A possible role for human papillomaviruses and c-myc, c-Ha-ras, and p53 gene alterations in malignant cutaneous lesions from renal transplant recipients.
Cancer detection and prevention - 1 Jan 1996
Pelisson I, Soler C, Chardonnet Y, Euvrard S, Schmitt D
Abstract excerpt
Several years after transplantation, renal transplant recipients develop numerous cutaneous squamous cell carcinomas (SCC), in which human papillomaviruses (HPV) may be detected. Alterations in c-myc, c-Ha-ras, and p53 genes were studied in 34 SCC, in correlation with the presence of HPV. In situ hybridization (ISH) and polymerase chain reaction (PCR) showed that many SCC contained several HPV types infecting...
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