Article
Lack of HLA-G soluble isoforms in Graves-Basedow thyrocytes and complete cDNA sequence of the HLA-G*01012 allele.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Aug 1998
Castro M J, Morales P, Catálfamo M, Fernández-Soria V, Suárez B, Varela P, Pérez-Blas M, Alvarez M, Jaraquemada D, Arnaiz-Villena A
Abstract excerpt
The presence of HLA-G mRNA has been studied in thyroid follicular cells from autoimmune patients with Graves' disease. Investigating the possible role of the expression of the HLA-G gene in tissue inflammation, we have found four of the six HLA-G mRNA isoforms described: G1, G2, G3 and G4, but no...
Topics
- Alleles
- Alternative Splicing
- Cell Line
- Cells, Cultured
- DNA
- DNA, Complementary
- Graves Disease
- HLA Antigens
- HLA-G Antigens
- Histocompatibility Antigens Class I
- Humans
- Molecular Sequence Data
- RNA, Messenger
- Thyroid Gland