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Article

Association of HLA-G 3' untranslated region variants with type 1 diabetes mellitus.

Human immunology - 1 Apr 2016

de Albuquerque Rafael S, Mendes-Junior Celso Teixeira, Lucena-Silva Norma, da Silva Camila Leal Lopes, Rassi Diane Meire, Veiga-Castelli Luciana C, Foss-Freitas Maria Cristina, Foss Milton César, Deghaide Neifi Hassan Saloum, Moreau Philippe, Gregori Silvia, Castelli Erick C, Donadi Eduardo Antônio

Abstract excerpt

Besides the well recognized association of HLA-DRB1 and DQB1 alleles with type 1 diabetes mellitus (T1D), linkage studies have identified a gene region close to the non-classical class I HLA-G gene as an independent susceptibility marker. HLA-G is constitutively expressed in the endocrine compartment of the human pancreas and may play a role in controlling autoimmune responses. We evaluated the genetic diversity...

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Identifiers

PMID: 26883941
DOI: 10.1016/j.humimm.2016.02.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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