Article
Dopamine D4 receptor gene polymorphisms and neuroleptic response in schizophrenia.
Biological psychiatry - 15 Sept 1998
Hwu H G, Hong C J, Lee Y L, Lee P C, Lee S F
Abstract excerpt
BACKGROUND: Dopamine D4 receptor (DRD4) gene polymorphisms are associated with various pharmacologic activities. This study investigated whether polymorphisms of 48-bp tandem repeats in the exon 3 of the DRD4 gene are related to neuroleptic response. METHODS: The neuroleptic response at the acute stage of schizophrenia was assessed in 80 (48 men, 32 women) schizophrenic patients. The negative symptoms at...
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