Dopamine D4 receptor gene polymorphisms and neuroleptic response in schizophrenia.

doi:10.1016/s0006-3223(98)00134-6

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Article

Dopamine D4 receptor gene polymorphisms and neuroleptic response in schizophrenia.

Biological psychiatry - 15 Sept 1998

Hwu H G, Hong C J, Lee Y L, Lee P C, Lee S F

Abstract excerpt

BACKGROUND: Dopamine D4 receptor (DRD4) gene polymorphisms are associated with various pharmacologic activities. This study investigated whether polymorphisms of 48-bp tandem repeats in the exon 3 of the DRD4 gene are related to neuroleptic response. METHODS: The neuroleptic response at the acute...

Topics

Adult
Antipsychotic Agents
DNA
Female
Genotype
Humans
Male
Polymorphism, Genetic
Receptors, Dopamine D2
Receptors, Dopamine D4
Repetitive Sequences, Nucleic Acid
Schizophrenia
Schizophrenic Psychology

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