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Article

Clinical response to antipsychotic drug treatment: association study of polymorphisms in six candidate genes.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Sept 2012

Vehof Jelle, Burger Huibert, Wilffert Bob, Al Hadithy Asmar, Alizadeh Behrooz Z, Snieder Harold

Abstract excerpt

Pharmacogenetic studies have demonstrated significant associations between several candidate genes (DRD2, DRD3, 5HTR2A and 5HTR2C, COMT and MTHFR) and antipsychotic drug response. The present study investigates the effect of nine polymorphisms in these genes for an association with antipsychotic...

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Source

Identifiers

PMID: 22386772
DOI: 10.1016/j.euroneuro.2012.01.006

Genes

MTHFR
DRD3
COMT
DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-22386772-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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