Article
Dopamine D2 receptor gene polymorphisms predict well the response to dopamine antagonists at therapeutic dosages in patients with schizophrenia.
Psychiatry and clinical neurosciences - 1 Apr 2007
Sakumoto Noboru, Kondo Tsuyoshi, Mihara Kazuo, Suzuki Akihito, Yasui-Furukori Norio
Abstract excerpt
Previous reports have shown that both A1 allele carriers of TaqI A and Del allele non-carriers of -141C Ins/Del for dopamine D(2) receptor (DRD(2)) gene polymorphisms have a better antipsychotic drug response. The present study aimed to examine the validity of a combination of these two DRD(2) polymorphisms as predictors for response to DRD(2) antagonists. The subjects consisted of 49 acutely exacerbated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
