Article
DRD4 exon III polymorphism and response to risperidone in Israeli adolescents with schizophrenia: a pilot pharmacogenetic study.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 May 2003
Zalsman Gil, Frisch Amos, Lev-Ran Shaul, Martin Andrés, Michaelovsky Elena, Bensason Daniela, Gothelf Doron, Nahshoni Eitan, Tyano Samuel, Weizman Abraham
Abstract excerpt
This study examined the possible association between the polymorphism in the dopamine receptor DRD4 gene and response to risperidone among 24 Israeli Jewish adolescent inpatients with first-episode schizophrenia. Response was categorically determined by a change of >40% on the Brief Psychiatric Rating Scale (BPRS). No significant association was found between the DRD4 genotype and clinical response, although...
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