Article
The mRNA export factor Npl3 mediates the nuclear export of large ribosomal subunits.
EMBO reports - 30 Sept 2011
Hackmann Alexandra, Gross Thomas, Baierlein Claudia, Krebber Heike
Abstract excerpt
The nuclear export of large ribonucleoparticles is complex and requires specific transport factors. Messenger RNAs are exported through the RNA-binding protein Npl3 and the interacting export receptor Mex67. Export of large ribosomal subunits also requires Mex67; however, in this case, Mex67 binds directly to the 5S ribosomal RNA (rRNA) and does not require the Npl3 adaptor. Here, we have discovered a new...
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