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Article

Successful isolation of a rat chromosome 1 blood pressure quantitative trait locus in reciprocal congenic strains.

Hypertension (Dallas, Tex. : 1979) - 1 Oct 1998

Frantz S A, Kaiser M, Gardiner S M, Gauguier D, Vincent M, Thompson J R, Bennett T, Samani N J

Abstract excerpt

Linkage analyses in experimental crosses of hypertensive and normotensive rats have strongly suggested the presence of a quantitative trait locus (QTL) influencing blood pressure on rat chromosome 1, at or near the Sa gene. To confirm the presence of such a locus and move toward identification of the causative gene, we have developed, through targeted breeding over 10 generations using an Sa gene polymorphism to...

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Source

Identifiers

PMID: 9774356
DOI: 10.1161/01.hyp.32.4.639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Successful isolation of a rat chromosome 1 blood pressure quantitative trait locus in reciprocal congenic strains.PMID 9774356Read ↗

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