Successful isolation of a rat chromosome 1 blood pressure quantitative trait locus in reciprocal congenic strains.

doi:10.1161/01.hyp.32.4.639

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Article

Successful isolation of a rat chromosome 1 blood pressure quantitative trait locus in reciprocal congenic strains.

Hypertension (Dallas, Tex. : 1979) - 1 Oct 1998

Frantz S A, Kaiser M, Gardiner S M, Gauguier D, Vincent M, Thompson J R, Bennett T, Samani N J

Abstract excerpt

Linkage analyses in experimental crosses of hypertensive and normotensive rats have strongly suggested the presence of a quantitative trait locus (QTL) influencing blood pressure on rat chromosome 1, at or near the Sa gene. To confirm the presence of such a locus and move toward identification of...

Topics

Animals
Animals, Congenic
Blood Pressure
Chromosome Mapping
Genotype
Hypertension
Lod Score
Male
Quantitative Trait, Heritable
Rats
Rats, Inbred SHR
Rats, Inbred WKY

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