Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Kidney specificity of rat chromosome 1 blood pressure quantitative trait locus region.

Hypertension (Dallas, Tex. : 1979) - 1 Sept 2002

Clemitson Jenny-Rebecca, Pratt Julian R, Frantz Simon, Sacks Steven, Samani Nilesh J

Abstract excerpt

Rat chromosome 1 has a region containing loci that influence blood pressure. In the present study, we investigated whether these loci mediate their effect via the kidney. Taking advantage of the histocompatibility between a congenic strain (WKY.SHR-Sa, which contains the relevant chromosomal region from the spontaneously hypertensive rat) and its parental strain, the Wistar-Kyoto rat (WKY), we compared the effect...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Congenic
Share to Chromosomes
Share to Creatinine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kidney Transplantation

Share to Organ Size

Share to Rats, Inbred SHR

Share to Rats, Inbred WKY

Source

Identifiers

PMID: 12215469
DOI: 10.1161/01.hyp.0000029106.10586.4c

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Kidney specificity of rat chromosome 1 blood pressure quantitative trait locus region.PMID 12215469Read ↗

Successful isolation of a rat chromosome 1 blood pressure quantitative trait locus in reciprocal congenic strains.Semantic proximity Read ↗

Genetic susceptibility to hypertension-induced renal damage in the rat. Evidence based on kidney-specific genome transfer.Semantic proximity Read ↗

Genetic isolation of a chromosome 1 region affecting susceptibility to hypertension-induced renal damage in the spontaneously hypertensive rat.Semantic proximity Read ↗

Genetic effects of blood pressure quantitative trait loci on hypertension-related organ damage: evaluation using multiple congenic strains.Semantic proximity Read ↗

Kidney-specific chromosome transfer in genetic hypertension: the Dahl hypothesis revisited.Semantic proximity Read ↗

Newborn and adult recombinant inbred strains: a tool to search for genetic determinants of target organ damage in hypertension.Semantic proximity Read ↗

Evidence of gene-gene interactions in the genetic susceptibility to renal impairment after unilateral nephrectomy.Semantic proximity Read ↗

Genetic dissection of region around the Sa gene on rat chromosome 1: evidence for multiple loci affecting blood pressure.Semantic proximity Read ↗

Isolation of a chromosome 1 region that contributes to high blood pressure and salt sensitivity.Semantic proximity Read ↗

Congenic substitution mapping excludes Sa as a candidate gene locus for a blood pressure quantitative trait locus on rat chromosome 1.Semantic proximity Read ↗

Dissection of a quantitative trait locus for genetic hypertension on rat chromosome 10.Semantic proximity Read ↗

Genetic Dissection of a Blood Pressure Quantitative Trait Locus on Rat Chromosome 1 and Gene Expression Analysis Identifies SPON1 As a Novel Candidate Hypertension GeneSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.