Article
Genetic mapping of two blood pressure quantitative trait loci on rat chromosome 1.
The Journal of clinical investigation - 1 Feb 1996
Gu L, Dene H, Deng A Y, Hoebee B, Bihoreau M T, James M, Rapp J P
Abstract excerpt
A genetic map for rat chromosome 1 was constructed using 66 microsatellite markers typed on either or both of two populations derived from inbred Dahl salt-sensitive (S) rats: F2(LEW x S) n = 151, and F2(WKY x S) n = 159. These populations had been raised on a high salt (8% NaCl) diet. Systolic blood pressure and heart weight were found to be genetically linked to two separate regions on rat chromosome 1 in the...
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