Article
Colonic cancer in a 34-yr-old woman: should it prompt microsatellite instability studies and mismatch repair gene testing?
The American journal of gastroenterology - 1 Oct 1998
Claro I, Cravo M, Glória L, Gaspar C, Albuquerque C, Lage P, Fidalgo P, Ramalho E, Chaves P, Cardoso P, Nobre Leitão C
Abstract excerpt
It remains debatable whether young patients with colorectal tumors should undergo genetic testing with the aim of identifying new hereditary nonpolyposis colorectal cancer families. We describe a case of a young woman with colon cancer with no clinical criteria of hereditary nonpolyposis colorect...
Topics
- Adult
- Colonic Neoplasms
- Colorectal Neoplasms, Hereditary Nonpolyposis
- DNA Repair
- DNA-Binding Proteins
- Female
- Humans
- Microsatellite Repeats
- MutS Homolog 2 Protein
- Mutation
- Pedigree
- Proto-Oncogene Proteins
- Risk Factors