Article
Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis.
Gastroenterology - 1 Apr 1996
Vasen H F, Wijnen J T, Menko F H, Kleibeuker J H, Taal B G, Griffioen G, Nagengast F M, Meijers-Heijboer E H, Bertario L, Varesco L, Bisgaard M L, Mohr J, Fodde R, Khan P M
Abstract excerpt
BACKGROUND & AIMS: Hereditary nonpolyposis colorectal cancer is characterized by early-onset colorectal cancer and the occurrence of various other cancers. The recent isolation of four mismatch repair genes responsible for hereditary nonpolyposis colorectal cancer allows for the identification of...
Topics
- Adolescent
- Adult
- Aged
- Colorectal Neoplasms, Hereditary Nonpolyposis
- DNA Mutational Analysis
- DNA Repair
- Family Health
- Female
- Genes
- Heterozygote
- Humans
- Intestinal Neoplasms
- Intestine, Small
- Male