Article
After hMSH2 and hMLH1--what next? Analysis of three-generational, population-based, early-onset colorectal cancer families.
International journal of cancer - 10 Nov 2002
Jenkins Mark A, Baglietto Laura, Dite Gillian S, Jolley Damien J, Southey Melissa C, Whitty Jonathan, Mead Leeanne J, St John D James B, Macrae Finlay A, Bishop D Timothy, Venter Deon J, Giles Graham G, Hopper John L
Abstract excerpt
The aim of our study was to examine the role of genetic factors on early-onset colorectal cancer after excluding the impact of germline mutations in the two major mismatch repair genes. A total of 131 incident probands, under 45 years at diagnosis of a first primary colorectal cancer selected fro...
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