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Article

Family history and molecular features of children, adolescents, and young adults with colorectal carcinoma.

Gut - 1 Aug 2005

Durno C, Aronson M, Bapat B, Cohen Z, Gallinger S

Abstract excerpt

BACKGROUND: Colorectal cancer is extremely rare in childhood. Published case series reporting children and adolescents with colorectal cancer have not focused on the underlying genetic aspects of the tumour or genetic susceptibility of the families. AIMS: We examined a cohort of patients with early onset colorectal cancer to determine whether a specific genetic predisposition could be elucidated. In particular,...

Topics

Adolescent
Adult
Child
Colorectal Neoplasms
DNA Repair
DNA, Neoplasm
Family Health
Female
Genetic Predisposition to Disease
Humans
Male
Microsatellite Repeats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Neoplasm Proteins

Neoplasms, Multiple Primary

Retrospective Studies

Source

Open in PubMed Open full text

Identifiers

PMID: 15845562
DOI: 10.1136/gut.2005.066092
PMCID: PMC1774876

Genes

MLH1
MSH2
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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