Article
[Genealogical research of hereditary nonpolyposis colorectal cancer].
Zhonghua wai ke za zhi [Chinese journal of surgery] - 1 Jun 2002
Wang Zhenjun, Zhao Bo, Xu Yufeng, Wan Yuanlian, Bu Dingfang, Huang Yanting
Abstract excerpt
OBJECTIVES To analyse the diagnosis and treatment of 24 hereditary nonpolyposis colorectal cancer (HNPCC) kindreds and report mismatch repair gene mutations. METHODS The diagnosis, treatment and follow-up of 24 HNPCC kindreds were reviewed retrospectively, cancer incidence and spectrum were recorded. Clinical characteristics and treatment were analyzed. Peripherial blood and genomic DNA were extracted from family...
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