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Article

Circular chromosome formation in a fission yeast mutant defective in two ATM homologues.

Nature genetics - 1 Oct 1998

Naito T, Matsuura A, Ishikawa F

Abstract excerpt

Telomeres, found at chromosomal ends, are essential for stable maintenance of linear chromosomes in eukaryotes. The ATM family of genes, including budding yeast TEL1 (refs 1,2), fission yeast rad3+ (ref. 3) and human ATM (ref. 4), have been reported to be involved in telomere length regulation, a...

Topics

Ataxia Telangiectasia Mutated Proteins
Base Sequence
Cell Cycle Proteins
Chromosomes, Fungal
DNA-Binding Proteins
Electrophoresis, Gel, Pulsed-Field
Flow Cytometry
Humans
Leucine Zippers
Molecular Sequence Data
Mutation
Protein Serine-Threonine Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proteins

Schizosaccharomyces

Spores, Fungal

Telomere

Tumor Suppressor Proteins

Source

Identifiers

PMID: 9771717
DOI: 10.1038/2517

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9771717-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Circular chromosome formation in a fission yeast mutant defective in two ATM homologues.PMID 9771717Read ↗

Regulation of genome stability by TEL1 and MEC1, yeast homologs of the mammalian ATM and ATR genes.Semantic proximity Read ↗

Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres.Semantic proximity Read ↗

Fission Yeast Tel1ATM and Rad3ATR Promote Telomere Protection and Telomerase RecruitmentSemantic proximity Read ↗

Analysis of alternative lengthening of telomere markers in BRCA1 defective cells.Semantic proximity Read ↗

Extra-chromosomal telomeric DNA in cells from Atm-/- mice and patients with ataxia-telangiectasiaSemantic proximity Read ↗

Integrity of human YACs during propagation in recombination-deficient yeast strains.Semantic proximity Read ↗

Recombination at long mutant telomeres produces tiny single- and double-stranded telomeric circles.Semantic proximity Read ↗

Recombination and the Tel1 and Mec1 checkpoints differentially effect genome rearrangements driven by telomere dysfunction in yeast.Semantic proximity Read ↗

The fission yeast bromodomain protein Bdf2 is required for the growth of cells with circular chromosomes.Semantic proximity Read ↗

Roles of the checkpoint sensor clamp Rad9-Rad1-Hus1 (911)-complex and the clamp loaders Rad17-RFC and Ctf18-RFC in Schizosaccharomyces pombe telomere maintenance.Semantic proximity Read ↗

TEL+CEN antagonism on plasmids involves telomere repeat sequences tracts and gene products that interact with chromosomal telomeres.Semantic proximity Read ↗

Fission yeast strains with circular chromosomes require the 9-1-1 checkpoint complex for the viability in response to the anti-cancer drug 5-fluorodeoxyuridine.Semantic proximity Read ↗

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