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Article

Roles of the checkpoint sensor clamp Rad9-Rad1-Hus1 (911)-complex and the clamp loaders Rad17-RFC and Ctf18-RFC in Schizosaccharomyces pombe telomere maintenance.

Cell cycle (Georgetown, Tex.) - 1 Jun 2010

Khair Lyne, Chang Ya-Ting, Subramanian Lakxmi, Russell Paul, Nakamura Toru M

Abstract excerpt

While telomeres must provide mechanisms to prevent DNA repair and DNA damage checkpoint factors from fusing chromosome ends and causing permanent cell cycle arrest, these factors associate with functional telomeres and play critical roles in the maintenance of telomeres. Previous studies have established that Tel1 (ATM) and Rad3 (ATR) kinases play redundant but essential roles for telomere maintenance in fission...

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Source

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Identifiers

PMID: 20505337
DOI: 10.4161/cc.9.11.11920
PMCID: PMC3133598

Genes

ATR
ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Roles of the checkpoint sensor clamp Rad9-Rad1-Hus1 (911)-complex and the clamp loaders Rad17-RFC and Ctf18-RFC in Schizosaccharomyces pombe telomere maintenance.PMID 20505337Read ↗

Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres.Semantic proximity Read ↗

Rad4TopBP1, a scaffold protein, plays separate roles in DNA damage and replication checkpoints and DNA replication.Semantic proximity Read ↗

Fission Yeast Tel1ATM and Rad3ATR Promote Telomere Protection and Telomerase RecruitmentSemantic proximity Read ↗

Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length.Semantic proximity Read ↗

A kinase-independent role for the Rad3(ATR)-Rad26(ATRIP) complex in recruitment of Tel1(ATM) to telomeres in fission yeast.Semantic proximity Read ↗

Tpz1-Ccq1 and Tpz1-Poz1 interactions within fission yeast shelterin modulate Ccq1 Thr93 phosphorylation and telomerase recruitment.Semantic proximity Read ↗

Human and mouse homologs of Schizosaccharomyces pombe rad1(+) and Saccharomyces cerevisiae RAD17: linkage to checkpoint control and mammalian meiosis.Semantic proximity Read ↗

Fission yeast shelterin regulates DNA polymerases and Rad3(ATR) kinase to limit telomere extension.Semantic proximity Read ↗

The Caenorhabditis elegans Rad17 homolog HPR-17 is required for telomere replication.Semantic proximity Read ↗

Coordinated functions of WSS1, PSY2 and TOF1 in the DNA damage response.Semantic proximity Read ↗

Rad4TopBP1 associates with Srr2, an Spc1 MAPK-regulated protein, in response to environmental stress.Semantic proximity Read ↗

Mammalian Rad9 plays a role in telomere stability, S- and G2-phase-specific cell survival, and homologous recombinational repair.Semantic proximity Read ↗

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