Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres.

doi:10.1093/genetics/161.4.1437

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Article

Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres.

Genetics - 1 Aug 2002

Nakamura Toru M, Moser Bettina A, Russell Paul

Abstract excerpt

Telomeres, the ends of linear chromosomes, are DNA double-strand ends that do not trigger a cell cycle arrest and yet require checkpoint and DNA repair proteins for maintenance. Genetic and biochemical studies in the fission yeast Schizosaccharomyces pombe were undertaken to understand how checkpoint and DNA repair proteins contribute to telomere maintenance. On the basis of telomere lengths of mutant...

Topics

Cell Cycle Proteins
Checkpoint Kinase 2
DNA Ligases
Endonucleases
Epistasis, Genetic
Exodeoxyribonucleases
Fungal Proteins
Genes, cdc
Intracellular Signaling Peptides and Proteins
Mutation
Protein Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Serine-Threonine Kinases

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Schizosaccharomyces

Schizosaccharomyces pombe Proteins

Telomere

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Identifiers

PMID: 12196391
DOI: 10.1093/genetics/161.4.1437
PMCID: PMC1462227

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