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Article

The fission yeast bromodomain protein Bdf2 is required for the growth of cells with circular chromosomes.

Bioscience, biotechnology, and biochemistry - 24 Jan 2022

Yasuda Misaki, Habib Ahmed G K, Sugiura Kanako, Shamim Hossain Mohammad, Ueno Masaru

Abstract excerpt

Circular chromosomes have frequently been observed in tumors of mesenchymal origin. In the fission yeast Schizosaccharomyces pombe, deletion of pot1+ results in rapid telomere loss, and the resulting survivors have circular chromosomes. Fission yeast has 2 bromodomain and extra-terminal (BET) proteins, Bdf1 and Bdf2; both are required for maintaining acetylated histones. Here, we found that bdf2, but not bdf1,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 34918022
DOI: 10.1093/bbb/zbab215

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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